highlighting the importance of looking beyond hormones and paying attention to heart health, bone strength, muscle, metabolism, brain health, sleep, and overall wellness during midlife.

What Should You Be Paying Attention to in Midlife?

October 09, 2026•19 min read
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Conversation Takeaways

By the end of our conversation, I want you to understand why your health in your 40s and 50s is about much more than managing menopause symptoms, how your heart, bones, muscles, metabolism, brain, sleep and sexual health fit into this season of your life, and why understanding your health matters more than simply collecting more health information.

Most importantly, I want you to begin asking a different question. Instead of only asking, “What are my hormones doing?” I want you to begin asking, “What should I actually understand about my health now?”

I Think We Need to Widen the Conversation

I want to have a slightly different conversation with you today because lately I have been thinking about how much the conversation around women's health has changed.

For years, women couldn't get anyone to talk about menopause. Women were having hot flashes, waking up at 3:00 in the morning, noticing changes in their mood, their bodies, their periods and their ability to concentrate, and too often they were told that everything was normal, they were too young for menopause, or they simply needed to learn to live with it.

Now the pendulum has swung in another direction.

We are talking about estrogen at breakfast, progesterone at lunch and testosterone over cocktails. We are comparing patches with our girlfriends, sending one another Instagram reels about cortisol, and wondering whether our aching knees are actually trying to tell us that we need more estrogen.

And you know what? In many ways, I am thrilled about this.

Women are finally talking about their bodies. They're asking questions. They're advocating for themselves. They're walking into healthcare appointments knowing words like perimenopause, estradiol and progesterone. They're refusing to accept that feeling miserable is simply the price of getting older.

That is progress.

But I also think something interesting has happened along the way.

We have become so focused on hormones that sometimes we forget there is an entire woman attached to them.

And that's the conversation I want to have with you today.

Because if you're somewhere in your 40s, 50s or beyond, I don't only want you asking whether you're in perimenopause or whether you need estrogen. I want you asking a much bigger question:

What should I actually understand about my health now?

Those are two very different conversations.

The Question Women Know to Ask

I see this all the time in practice.

A woman comes into an appointment and she already has a working theory about what is happening. She's exhausted. She's waking up in the middle of the night. Her brain doesn't feel as sharp as it used to. Her weight has changed even though she doesn't believe she's doing anything differently. Her joints hurt. Her patience seems to have packed a bag and left town.

And she says, “I think I'm in perimenopause and I want to talk about HRT.”

Or maybe she's already taking hormone therapy and she's wondering whether she needs more estrogen because something still doesn't feel right.

That's the conversation she knows to have.

And I understand why.

If you spend any amount of time online in the women's health world right now, you are going to hear a lot about hormones. Depending on what the algorithm decides you need that particular Tuesday, you may learn that estrogen is responsible for your brain, your bones, your heart, your skin, your libido, your joints, your metabolism and possibly why your neighbor's dog barked at you.

Okay, I'm exaggerating.

A little.

But the message women are receiving is powerful: hormones matter.

And they absolutely do.

What I don't want us to do, however, is take a women's-health conversation that was once far too small and simply replace it with a different conversation that is still too small.

Because your health at midlife is bigger than your estrogen level.

Something Important Is Happening in Women's Health

This isn't simply something I'm noticing in my own practice. The larger women's-health conversation is beginning to widen too.

The National Institutes of Health has been looking at the menopausal transition as an important period for women's long-term health, not simply because women may experience hot flashes or changes in their menstrual cycles, but because this season intersects with things like cholesterol, blood pressure, weight, bone density, sleep, sexual health and emotional health.

Researchers are also continuing to look at cardiovascular health, bone health, cognitive health and metabolic changes across this transition.

And I think that's important because it changes the question from “How do we make menopause go away?” to something much more useful:

“What can this season teach me about what my body needs now?”

I also want to be careful here because I do not want you listening to this episode thinking, Well, this is fabulous. I came here worried about hot flashes and now Michele has given me seven diseases to worry about.

No.

That is not what we're doing.

Menopause is a normal biological transition. It isn't a disease. And getting older isn't something we need to diagnose or fix.

But our biology does change.

And when biology changes, it makes sense to understand what those changes might mean for the rest of our health.

That isn't fear.

That's awareness.

And awareness gives us choices.

This Is Why I Created Feel Like Yourself Again

If you're listening to this thinking, This is exactly my problem. I have all these little pieces of health information, but I don't know how they fit together, that's exactly why I created my free five-day experience, Feel Like Yourself Again: Learn to Read the Story Your Body Has Been Telling.

It isn't five days of me handing you another list of things you're supposed to fix. In fact, I created it because I think most women already have enough lists.

We start somewhere much more useful.

We start by helping you learn how to look at your body as a whole story rather than a collection of unrelated symptoms.

Because once you begin seeing patterns instead of isolated problems, you can start asking much better questions about your health.

And that is where health confidence begins.

You can join Feel Like Yourself Again here.

Now let's keep going, because there are several parts of your health that I think deserve a place in the midlife conversation right alongside hormones.

Your Heart Is Part of the Menopause Conversation

Let's start with your heart, not because I want to scare you, but because I think cardiovascular health is one of the best examples of an important women's-health conversation that often gets overshadowed by symptoms.

Recent research highlighted by the American Heart Association has continued to examine how cardiovascular health changes around the menopause transition, including changes involving cholesterol, blood sugar and other cardiovascular-health measures.

That does not mean perimenopause suddenly gives a woman heart disease.

Life is much more complicated than that.

Age is happening at the same time. Genetics matter. Blood pressure matters. Smoking matters. Nutrition matters. movement matters. sleep matters. family history matters. Metabolic health matters.

In other words, your whole story matters.

That's why this season can be a useful time to stop and ask some very ordinary questions that we sometimes forget to ask while we're busy discussing estrogen patches.

Do you know what your blood pressure generally runs? Do you know what has been happening with your cholesterol over time rather than simply whether the last result was marked “normal”? Do you know your blood sugar or A1C when it's appropriate for you to have it checked? Do you know whether cardiovascular disease runs in your family?

Those questions may not be nearly as exciting on Instagram as “Three signs your estrogen is crashing!”

But they matter.

And sometimes the least glamorous pieces of health information are the ones worth knowing.

Your Bones Are Quiet Until They Aren't

Then there are your bones.

This is one of those areas of women's health that simply isn't very good at marketing itself.

Hot flashes announce themselves. A disappearing period gets your attention. Vaginal dryness usually makes its presence known.

Bone loss?

Bone loss is quiet.

You don't wake up one morning and think, Wow, I can really feel my bone mineral density declining today.

Yet we know that bone health becomes increasingly important as women move through menopause and beyond, and estrogen is one part of that story.

So I don't only want you thinking about estrogen in terms of whether it helps your symptoms. I want you to understand that your bones deserve some attention too.

That means understanding your own risk factors, knowing whether osteoporosis runs in your family, paying attention to nutrition and movement, and having conversations with your healthcare provider about when bone-density screening is appropriate for you.

And notice what I'm not doing here.

I'm not telling every woman listening that she needs exactly the same test at exactly the same age.

That's the opposite of what I want you to learn.

Your healthcare should be informed by your story, not by somebody else's Instagram carousel.

I Want Us Talking Much More About Muscle

Muscle is another part of women's health that I think deserves a much bigger conversation.

For years, women were taught to think about exercise primarily in terms of burning calories. We exercised to lose weight, fit into our jeans or compensate for something we ate.

I want to change that conversation.

Your muscle isn't just there to make your arms look nice in a sleeveless dress, although I am certainly not opposed to that benefit.

Muscle is part of how you move through the world. It contributes to strength, physical function and metabolic health, and maintaining strength becomes increasingly important as we age.

So when a woman tells me that she's walking every day, I think that's wonderful. Please keep walking.

But I also want to know what she's doing to maintain her strength.

And no, I'm not asking you to start training for the Olympics.

I want you strong enough to carry your groceries, pick up your grandchildren, haul your suitcase into the overhead compartment and get yourself off the floor without having to negotiate with God first.

That is women's health too.

Metabolism Is More Than the Number on Your Scale

Now we have to talk about the subject that gets almost everyone's attention.

Weight.

Almost every woman I see wants to talk about weight at some point, and I understand why.

Your body begins behaving differently. You swear you're eating the same way. You're exercising. You're trying to do everything you're “supposed” to do, and suddenly your favorite pants have betrayed you.

But I want to widen this conversation too.

Changes in body composition, fat distribution and the way our bodies use energy can occur as we move through midlife. At the same time, sleep, stress, activity, nutrition, muscle mass, genetics and aging are all part of the metabolic picture.

That's why I don't want the entire conversation about metabolic health reduced to:

“How do I get these ten pounds off?”

I want us thinking about what is happening underneath that number too.

How is your blood sugar doing? What is happening with your blood pressure? What is happening with your cholesterol? Are you maintaining muscle? How are you eating most of the time? Are you moving your body? Are you sleeping?

The scale gives you one piece of information.

It does not give you your entire metabolic story.

And sometimes when we become obsessed with one number, we miss the more important story happening around it.

Your Brain Deserves More Than “It's Just Menopause”

Brain fog is one of the most common things women talk to me about.

They tell me, “I can't find my words anymore,” or, “I walk into a room and forget why I'm there,” or, “I can't concentrate the way I used to.”

Sometimes they say something that I hear quite often:

“My brain doesn't feel like mine.”

Because menopause awareness has increased, women are understandably connecting some of these changes with hormonal shifts.

And hormonal changes may absolutely be part of the picture.

But this is another place where I don't want us making hormones responsible for everything.

Sleep affects cognition. Stress affects cognition. Mood affects cognition. Some medications can affect cognition. Thyroid conditions, anemia and other health issues can produce symptoms that overlap with what women are experiencing during perimenopause.

Which is why the question I want us asking isn't simply:

“Which hormone causes brain fog?”

I want us asking:

“What is happening in this woman's whole story?”

That question gives us somewhere much more useful to go.

Sleep Is Not a Luxury Item

And then we come to sleep.

You knew I wasn't going to let you leave without talking about sleep.

One of the things I appreciate about the broader research conversation happening around midlife women is that researchers are increasingly acknowledging something women already know very well: menopause isn't occurring in a laboratory.

It's occurring while you're raising children, helping adult children, caring for aging parents, managing a career, running a business, navigating relationships and trying to remember whether you actually switched the laundry from the washer to the dryer.

You're running a meeting at 10:00, calling Mom's doctor at noon, answering seventeen emails at 4:30 and then lying wide awake at 3:07 in the morning wondering why your cortisol has apparently decided this would be an excellent time for a staff meeting.

This is exactly why I don't teach women's health in a biological vacuum.

Sleep is happening inside your life.

And when sleep starts falling apart, it can ripple into your mood, your cognition, your energy, your appetite, your recovery and your ability to do any of the healthy things somebody has just told you that you “should” be doing.

Sometimes the answer isn't another thing to add to your list.

Sometimes we need to understand what is already draining the system.

And Please, Can We Talk About Vaginal, Urinary and Sexual Health?

There is another area women sometimes don't realize belongs in the larger health conversation: vaginal, urinary and sexual health.

Dryness, pain with sex, changes in libido, urinary urgency, recurrent urinary tract infections and leaking when you sneeze, run or laugh are things women may quietly tolerate for years because they assume this is simply what happens when you get older.

And ladies, crossing your legs before you sneeze is not technically a pelvic-health treatment plan.

These symptoms deserve a real conversation with your healthcare provider.

One of the things I want women to understand is that something can be common without being something you simply have to accept.

Your sexual health matters.

Your vaginal health matters.

Your urinary health matters.

And you shouldn't have to feel embarrassed about bringing any of those things into the conversation.

And Then There Are the Labs

There is one more thing I'm noticing both in practice and in the conversations women are having online.

Women are arriving with lists.

Sometimes the list came from social media. Sometimes it came from a podcast. Sometimes it came from another health professional online. And very often it came from a friend who said, “You need to have all of these checked.”

And I completely understand why women are doing this.

When you've spent years feeling as though nobody is looking deeply enough, having a list can make you feel like you're finally taking control of your health.

But here's the one thing I want you to remember for today:

More testing doesn't automatically equal better healthcare.

Before you ask for a test, I want you to understand what question you're trying to answer.

That's it.

I'm actually going to stop there because we're going to have an entire conversation about this next.

I'm introducing a new recurring conversation on the show called Ask Michele, where I'm going to take the kinds of questions women are actually asking me and talk through them with you the way I would if you were sitting across from me.

And our very first question is:

“Michele, my friend told me I need all these labs. Do I?”

Oh ladies, do I have some thoughts about that one.

Because that conversation isn't really going to be about making a perfect list of labs.

It's going to be about something much bigger.

It's going to be about learning how to participate in your healthcare without feeling like you have to become your own healthcare provider.

And that is what I call Health Independence.

We'll talk about that next.

HRT Can Be Part of Your Health Story Without Becoming the Whole Story

Before we finish, I want to make something very clear because I don't want this conversation interpreted as anti-HRT.

I prescribe hormone therapy.

I believe hormone therapy can be incredibly helpful for appropriately selected women, and I have watched women feel dramatically better when they receive the right treatment.

But HRT does not relieve us from paying attention to the rest of our health.

And it doesn't mean every new symptom is asking for more estrogen.

You can be taking HRT and still need to understand what is happening with your cardiovascular health. You can be taking HRT and still need to think about your bones and your muscle. You can be taking HRT and still need to address your sleep, keep up with appropriate health screenings and understand what is happening with your blood pressure, cholesterol and blood sugar.

And you can be taking HRT and have something going on that has absolutely nothing to do with menopause.

That's why I want us to resist turning hormone therapy into the answer to every question.

HRT is a tool.

Sometimes it is an excellent tool.

But it is not your entire health strategy.

This Is the Part of Women's Health I Want Us to Get Back To

I've spent about thirty years taking care of women, and I love that menopause is finally having its moment.

I truly do.

But I don't want the next generation of women to become incredibly educated about estrogen while remaining disconnected from the rest of their health.

I want something bigger for us.

I want you to know your body well enough to recognize when something has changed. I want you to understand the health numbers that actually matter to you and why they matter. I want you to know your family history. I want you to recognize patterns instead of chasing individual symptoms. I want you to understand why your healthcare provider is recommending something instead of simply nodding because someone in a white coat told you to do it.

And I want you walking into your healthcare appointments with better questions.

Not because I expect you to become your own doctor.

Please don't.

Some of us went to school for a very long time for that job.

What I want is for you to become an informed participant in your own health.

There is a very big difference.

So What Should You Actually Be Paying Attention To?

If you were sitting across from me with a cup of tea and asked, “Okay Michele, but where do I even start?” I wouldn't hand you a 42-item midlife wellness checklist.

Because then you'd leave our conversation needing treatment for stress.

I'd ask you to begin with your story.

I'd want to know what has changed and what keeps showing up. I'd want to know how you're sleeping, how your energy feels throughout the day and whether you're maintaining your strength. I'd want to know what you understand about your blood pressure, cholesterol and blood sugar, what you know about your bone-health risk factors and whether you're keeping up with the health screenings that are appropriate for you.

I'd want to know whether your vaginal, urinary or sexual health has changed, what health conditions run in your family and whether there is something happening in your body right now that you simply don't understand.

And then I would ask you one of my favorite questions:

“What are you noticing?”

Because that's where I want you to start.

Not with panic.

Not with perfection.

Not with trying to monitor every system in your body like you're running mission control at NASA.

With curiosity.

With awareness.

With understanding.

This Is Also Why Feel Like Yourself Again Matters

If you've spent the last few years trying to solve one symptom at a time, this is where I want to invite you again into my free five-day experience, Feel Like Yourself Again: Learn to Read the Story Your Body Has Been Telling.

Because the entire idea behind it is what we've talked about today.

Your symptoms aren't random little problems floating around independently. Your hormones don't live in a vacuum. Your sleep doesn't live in a vacuum. Your stress doesn't live in a vacuum. Your metabolism doesn't live in a vacuum.

You are one whole woman.

And once you begin seeing the whole story, you can stop chasing every new headline, reel and health trend and start understanding which questions actually belong to you.

You can join Feel Like Yourself Again free here

The Conversation I Want Women to Have Now

For a long time, women were told far too little about menopause.

We needed to change that.

And thankfully, we are changing it.

But I think we're ready for the next conversation now.

Not just:

“What are my hormones doing?”

But:

“What is happening in my health during this season of my life, and what deserves my attention?”

Because your heart matters, but so do your bones. Your muscles matter, but so does your metabolism. Your brain matters. Your sleep matters. Your sexual health matters. Your emotional health matters.

And yes, your hormones matter.

They aren't competing priorities.

They're all part of the same woman.

So maybe the goal of midlife isn't to become obsessed with everything that could possibly go wrong.

Maybe the goal is something much more useful than that.

Know your body well enough to recognize what deserves your attention.

Because when you understand your body, you can ask better questions. When you ask better questions, you can have better conversations with the people caring for you. And when you understand why you're making the health decisions you're making, you don't have to depend on the latest Instagram reel, your friend's lab list or whichever health headline happens to land in your inbox that morning to tell you what your body needs.

You become an informed participant in your health.

And that, to me, is where Health Independence begins.

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